Staphylococcal scalded skin syndrome - Стафилококов Синдром На Попарена Кожа
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Бебе с Стафилококов Синдром На Попарена Кожа (Staphylococcal scalded skin syndrome)
relevance score : -100.0%
ReferencesStaphylococcal Scalded Skin Syndrome е състояние, при което кожата се отделя поради токсини, произведени от някои видове бактерии Staphylococcus. Не е често срещано при деца над шест години. Може да се появи и при възрастни с отслабена имунна система или сериозни бъбречни проблеми. Основната характеристика е обширно лющене на кожата след възпаление. Тежестта варира от няколко мехура до широко разпространена загуба на кожа, което може да доведе до значително падане на телесната температура и нестабилно кръвно налягане.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
Момченце на 10 месеца дойде с хрема и не се храни добре. Лекарите казаха, че е инфекция на горните дихателни пътища. Два дни по-късно той се върна, защото не се подобряваше и имаше нови проблеми като подуто лице и раздразнена кожа около устата. През следващите два дни момчето се влоши. Ръцете и краката му се подуха и кожата му започна да се отлепва. Обратно в болницата лекарите забелязаха червен обрив по лицето и в гънките на кожата му, който побеляваше при допир. Те му поставиха диагноза staphylococcal scalded skin syndrome (SSSS) и му започнаха антибиотици през вената.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
2‑годишно момиче се появи с обрив по цялото тяло, който се разви в продължение на 48 часа след ухапвания от насекоми по лицето й предния ден. При прегледа имаше широко разпространен обрив, съставен от малки подутини, които се сляха, и при леко разтриване кожата показваше положителен признак на Николски. Нямаше увреждане на лигавиците. Кръвните тестове не показаха признаци на инфекция.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
Синдромът се индуцира от епидермолитични екзотоксини (ексфолиатин) А и В, които се отделят от S. aureus. Прогнозата за стафилококовия синдром на попарена кожа (staphylococcal scalded skin syndrome) при деца е отлична – пълно излекуване се постига в рамките на 10 дни от започване на лечението и без значителни белези. Въпреки това, синдромът трябва внимателно да се диференцира от токсичната епидермална некролиза, която има лоша прогноза.
○ Диагностика и лечение
Грешната диагноза – например като атопичен дерматит – и прилагането на стероиден мехлем влошават лезиите. Моля, потърсете медицинска помощ възможно най‑скоро, докато се прилага антибиотичен мехлем.
#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)